Search on: 2-OXOISOVALERATE DEHYDROGENASE (ACYLATING) 
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Descriptor English:   2-Oxoisovalerate Dehydrogenase (Acylating) 
Descriptor Spanish:   2-Oxoisovalerato Deshidrogenasa (Acilante) 
Descriptor Portuguese:   2-Oxoisovalerato Desidrogenase (Acilante) 
Tree Number:   D08.811.682.657.350.825
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50621 
Unique Identifier:   D050645 

Occurrence in VHL:
 

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